Euphol
Cat. No.：YN373084
| 产品名称: | Euphol |
| CAS No.: | 514-47-6 |
| Chemical Name: | α-Euphol; NSC 36571; Eupha-8,24-dienol; Eupha-8,24-dien-3β-ol; 5α-Eupha-8,24-dien-3β-ol; (+)-Eupha-8,24-dien-3β-ol; (+)-Euphol; 3α,14β,17βH-Lanosta-8,24-dien-3β-ol |
| Synonyms: | 大戟二烯醇 |
| 分子量: | 426.72 |
| 分子式: | C₃₀H₅₀O |
| SMILES: | C[C@@]1(CC2)[C@@](CC[C@]1([C@H](C)CC/C=C(C)/C)[H])(C)C3=C2[C@]4(C)[C@](CC3)([H])C(C)(C)[C@@H](O)CC4 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Euphol 是一种四环三萜醇，是从Euphorbia tirucalli的汁液中分离出来的，具有抗炎和免疫调节作用，具有口服活性。 Euphol 通过一种可逆机制抑制单酰基甘油脂肪酶 (MGL) 的活性，IC50=315 nM。 外周 MGL 抑制可调节内源性大麻素系统从而阻止炎症性疼痛的发展。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Dutra, R.C., et. al.: Biochem. Pharmacol., 83, 531 (2012)
Singh, G.B., et. al.: Planta Med., 55, 498 (1989)
