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Ginkgolide B

Cat. No.:YN373173

  • CAS No. :15291-77-7

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Ginkgolide B
      CAS No.: 15291-77-7
      Chemical Name: (1R,3S,3aS,4R,6aR,7aR,7bR,8S,10aS,11R,11aR)-3-(1,1-dimethylethyl)hexahydro-4,7b,11-trihydroxy-8-methyl-9H-1,7a-(epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3’,2’:3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione
      Synonyms:BN-52021
      分子量:424.40
      分子式:C₂₀H₂₄O₁₀
      SMILES:O[C@@H]1C(C2([C@H]3O)[C@](OC3=O)([H])O4)([C@@](O5)([H])C[C@H]2C(C)(C)C)C4(C5=O)[C@@](O)([C@@H]6C)[C@@]1([H])OC6=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Ginkgolide B (BN-52021) 是一种萜类物质,是银杏叶中的重要的活性物质之一。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Prescott, S.M., Zimmerman, G.A., and McIntyre, T.M.Platelet-activating factorJ. Biol. Chem.265(29),17381-17384(1990)

      Funkunaga, K., Ishii, S., Asano, K., et al.Single nucleotide polymorphism of human platelet-activating factor impairs G-protein activationJ. Biol. Chem.276(46),43025-43030(2001)

      Cho, H.J., and Nam, K.S.Inhibitory effect of ginkgolide B on platelet aggregation in a cAMP- and cGMP-dependent manner by activated MMP-9J. Biochem. Mol. Biol.40(5),678-683(2007)

      Aponte, M., Jiang, W., Lakkis, M., et al.Activation of PAF-receptor and pleiotropic effects on tyrosine phospho-EGFR/Src/FAK/paxillin in ovarian cancerCancer Res.68(14),5839-5848(2008)

      Shi-hai, X., and Dian-chun, F.Pharmacological action and mechanisms of ginkgolide BChin. Med. J. (Engl.)120(10),922-928(2007)

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