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JQ-1 (carboxylic acid)

Cat. No.：202592-23-2

  • CAS No. ：202592-23-2

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    • 产品名称: JQ-1 (carboxylic acid)
      CAS No.: 202592-23-2
      Chemical Name:
      Synonyms:JQ-1 carboxylic acid
      分子量:400.88
      分子式:C₁₉H₁₇ClN₄O₂S
      SMILES:ClC1=CC=C(C(C2=C(N3C4=NN=C3C)SC(C)=C2C)=N[C@H]4CC(O)=O)C=C1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Filippakopoulos, P., Qi, J., Picaud, S., et al.Selective inhibition of BET bromodomainsNature468(7327),1067-1073(2010)', 'Dawson, M.A., Kouzarides, T., and Huntly, B.J.Targeting epigenetic readers in cancerN. Engl. J. Med.367(7),647-657(2012)', 'Delmore, J.E., Issa, G.C., Lemieux, M.E., et al.BET bromodomain inhibition as a therapeutic strategy to target c-MycCell146(6),904-917(2011)', 'Mertz, J.A., Conery, A.R., Bryant, B.M., et al.Targeting MYC dependence in cancer by inhibiting BET bromodomainsProc. Natl. Acad. Sci. USA108(40),16669-16674(2011)', 'Dawson, M.A., Prinjha, R.K., Dittmann, A., et al.Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemiaNature478,529-533(2011)
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    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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