Mometasone furoate
Cat. No.：YN320788
CAS No. ：83919-23-7
| 产品名称: | Mometasone furoate |
| CAS No.: | 83919-23-7 |
| Chemical Name: | 9,21-dichloro-17-[(2-furanylcarbonyl)oxy]-11β-hydroxy-16α-methyl-pregna-1,4-diene-3,20-dione |
| Synonyms: | 糠酸莫米松; Sch32088 |
| 分子量: | 521.43 |
| 分子式: | C₂₇H₃₀Cl₂O₆ |
| SMILES: | C[C@@]12[C@](C(CCl)=O)(OC(C3=CC=CO3)=O)[C@H](C)C[C@@]1([H])[C@]4([H])CCC5=CC(C=C[C@]5(C)[C@@]4(Cl)[C@@H](O)C2)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Mometasone furoate (Sch32088) 是一种糖皮质激素受体 (glucocorticoid receptor) 激动剂，具有抗炎和抗过敏活性。Mometasone furoate 作为皮质类固醇类试剂，动物模型中，用于慢性皮肤湿疹和气道炎症以及哮喘的局部应用。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Lin, R., Elf, S., Shan, C., et al.6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signallingNat. Cell Biol.17(11),1484-1496(2015)
Altuntaş, E.E., Doğan, O.T., Saraç, B., et al.The effects of mometasone furoate and strontium chloride in a rat model of allergic rhinitisEar Nose Throat J.97(1-2),E1-E7(2018)
Ogawa, M.Dissociation of local anti-inflammatory effect and systemic effects of mometasone furoate in miceImmunopharmacol. Immunotoxicol.31(4),601-606(2009)
