TC-G 1005
Cat. No.：YN320409
CAS No. ：1415407-60-1
| 产品名称: | TC-G 1005 |
| CAS No.: | 1415407-60-1 |
| Chemical Name: | (4-Cyclopropyl-3,4-dihydro-1(2H)-quinoxalinyl)[4-(2,5-dimethylphenoxy)-3-pyridinyl]methanone; |
| Synonyms: | (4-环丙基-3,4-二氢-1(2H)-喹喔啉基)[4-(2,5-二甲基苯氧基)-3-吡啶基]甲酮 |
| 分子量: | 399.48 |
| 分子式: | C₂₅H₂₅N₃O₂ |
| SMILES: | O=C(C1=CN=CC=C1OC2=C(C=CC(C)=C2)C)N3C4=CC=CC=C4N(C5CC5)CC3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | TC-G 1005 是一种有效，选择性和口服活性的TGR5激动剂，激活 hTGR5 和 mTGR5 的EC50值分别为 0.72 和 6.2 nM。TC-G 1005 可降低小鼠体内葡萄糖水平。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Zhou, C., et al.: Med. Chem., 24, 2561-2572 (2015)
Duan, H., et al.: J. Med. Chem., 55, 10475 (2012)
