Cinaciguat hydrochloride

Cat. No.：646995-35-9

CAS No. ：646995-35-9

产品名称:	Cinaciguat hydrochloride
CAS No.:	646995-35-9
Chemical Name:
Synonyms:	BAY 58-2667 hydrochloride
分子量:	602.16
分子式:	C₃₆H₄₀ClNO₅
SMILES:	OC(C(C=C1)=CC=C1CN(CCCCC(O)=O)CCC(C=CC=C2)=C2OCC(C=C3)=CC=C3CCC4=CC=CC=C4)=O.[H]Cl
存储:	Please store the product under the recommended conditions in theCertificate of Analysis.
运输:	Room temperature in continental US; may vary elsewhere.

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Purity: 0.98

Stasch, J.P., Pacher, P., and Evgenov, O.V.Soluble guanylate cyclase as an emerging therapeutic target in cardiopulmonary diseaseCirculation123(20),2263-2273(2011)', 'Stasch, J.P., Schmidt, P., Alonso-Alija, C., et al.NO- and haem-independent activation of soluble guanylyl cyclase: Molecular basis and cardiovascular implications of a new pharmacological principleBr. J. Pharmacol.136,773-783(2002)', 'Irvine, J.C., Ganthavee, V., Love, J.E., et al.The soluble guanylyl cyclase activator bay 58-2667 selectively limits cardiomyocyte hypertrophyPLoS One7(11),1-11(2012)', 'Salloum, F.N., Das, A., Samidurai, A., et al.Cinaciguat, a novel activator of soluble guanylate cyclase, protects against ischemia/reperfusion injury: role of hydrogen sulfideAm. J. Physiol. Heart Circ. Physiol.302,H1347-H1354(2012)', 'Vandendriessche, B., Rogge, E., Goossens, V., et al.The soluble guanylate cyclase activator BAY 58-2667 protects against morbidity and mortality in endotoxic shock by recoupling organ systemsPLoS One8(9),1-10(2013)