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Adefovir

Cat. No.：106941-25-7

  • CAS No. ：106941-25-7

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    • 产品名称: Adefovir
      CAS No.: 106941-25-7
      Chemical Name:
      Synonyms:阿德福韦; GS-0393; PMEA
      分子量:273.19
      分子式:C₈H₁₂N₅O₄P
      SMILES:NC1=C2N=CN(CCOCP(O)(O)=O)C2=NC=N1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 0.98
    • Arimilli, M.N., Dougherty, J.P., Cundy, K.C., et al.Orally bioavailable acyclic nucleoside phosphonate prodrugs: Adefovir dipivoxil and bis(POC)PMPAAdvances in Antiviral Drug Design3,69-91(1999)', 'Laizure, S.C., Herring, V., Hu, Z., et al.The role of human carboxylesterases in drug metabolism: Have we overlooked their importance?Pharmacotherapy33(2),210-222(2013)', 'Holý, A., Votruba, I., Masojídková, M., et al.6-[2-(Phosphonomethoxy)alkoxy]pyrimidines with antiviral activityJ. Med. Chem.45(9),1918-1929(2002)', 'Rossi, L., Dominici, S., Serafini, S., et al.Pharmacokinetic and antiretroviral activity in mice of oral [P1,P2-bis[2-(adenin-9-yl)ethoxymethyl]phosphonate], a prodrug of 9-(2-phosphonylmethoxyethyl)adenineJ. Antimicrob. Chemother.50(3),365-374(2002)', 'Naesens, L., Balzarini, J., Bischofberger, N., et al.Antiretroviral activity and pharmacokinetics in mice of oral bis(pivaloyloxymethyl)-9-(2-phosphonylmethoxyethyl)adenine, the bis(pivaloyloxymethyl) ester prodrug of 9-(2-phosphonylmethoxyethyl)adenineAntimicrob. Agents Chemother.40(1),22-28(1996)
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