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Apabetalone

Cat. No.：1044870-39-4

  • CAS No. ：1044870-39-4

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    • 产品名称: Apabetalone
      CAS No.: 1044870-39-4
      Chemical Name:
      Synonyms:阿帕他隆; RVX-208; RVX000222
      分子量:370.40
      分子式:C₂₀H₂₂N₂O₅
      SMILES:COC1=CC(OC)=C(C(NC(C2=CC(C)=C(OCCO)C(C)=C2)=N3)=O)C3=C1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Filippakopoulos, P., Qi, J., Picaud, S., et al.Selective inhibition of BET bromodomainsNature468(7327),1067-1073(2010)', 'McLure, K.G., Gesner, E.M., Tsujikawa, L., et al.RVX-208, an inducer of ApoA-I in humans, is a BET bromodomain antagonistPLoS One8(12),1-12(2013)', 'Picaud, S., Wells, A., Felletar, I., et al.RVX-208, an inhibitor of BET transcriptional regulators with selectivity for the second bromodomainProc. Natl. Acad. Sci. USA110(49),19754-19759(2013)', 'Bailey, D., Jahagirdar, R., Gordon, A., et al.RVX-208: A small molecule that increases apolipoprotein A-I and high-density lipoprotein cholesterol in vitro and in vivoJ. Am. Coll. Cardiol.55(23),2580-2589(2010)', 'Jahagirdar, R., Zhang, H., Azhar, S., et al.A novel BET bromodomain inhibitor, RVX-208, shows reduction of atherosclerosis in hyperlipidemic ApoE deficient miceAtherosclerosis236(1),91-100(2014)
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