Rilpivirine
Cat. No.：YN250121
CAS No. ：500287-72-9
| 产品名称: | Rilpivirine |
| CAS No.: | 500287-72-9 |
| Chemical Name: | 4-[[4-[[4-[(1E)-2-cyanoethenyl]-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]-benzonitrile |
| Synonyms: | 利匹韦林; R278474; TMC278; DB08864 |
| 分子量: | 366.42 |
| 分子式: | C₂₂H₁₈N₆ |
| SMILES: | CC1=CC(/C=C/C#N)=CC(C)=C1NC2=CC=NC(NC3=CC=C(C=C3)C#N)=N2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Rilpivirine (R278474; TMC278) 是 HIV 的非核苷逆转录酶抑制剂。 |
| IC50和靶点: | |
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Garvey, L., and Winston, A.Rilpivirine: A novel non-nucleoside reverse transcriptase inhibitorExpert Opin. Drug Discov.18(7),1035-1041(2009)
Arainga, M., Edagwa, B., Mosley, R.L., et al.A mature macrophage is a principal HIV-1 cellular reservoir in humanized mice after treatment with long acting antiretroviral therapyRetrovirology14(1),17(2017)
