Zidovudine
Cat. No.：YN250713
CAS No. ：30516-87-1
| 产品名称: | Zidovudine |
| CAS No.: | 30516-87-1 |
| Chemical Name: | 3’-azido-3’-deoxy-thymidine |
| Synonyms: | 叠氮胸苷; Azidothymidine; AZT; ZDV |
| 分子量: | 267.24 |
| 分子式: | C₁₀H₁₃N₅O₄ |
| SMILES: | O=C(C(C)=CN1[C@@H](C2)O[C@@H]([C@H]2N=[N+]=[N-])CO)NC1=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Zidovudine 是一种核苷逆转录酶抑制剂 (NRTI)，有潜力用于 HIV 感染的研究。Zidovudine 增强 CRISPR/Cas9调节的编辑频率。 |
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Cihlar, T., and Ray, A.S.Nucleoside and nucleotide HIV reverse transcriptase inhibitors: 25 years after zidovudineAntiviral Res.85(1),39-58(2010)
Anderson, P.L., Nakuda, T.K., and Lichtenstein, K.A.The cellular pharmacology of nucleoside- and nucleotide-analogue reverse-transcriptase inhibitors and its relationship to clinical toxicitiesClin. Infect. Dis.38(5),743-753(2004)
Perno, C.-F., Yarchoan, R., Cooney, D.A., et al.Inhibition of human immunodeficiency virus (HIV-1/HTLV-IIIBa-L) replication in fresh and cultured human peripheral blood monocytes/macrophages by azidothymidine and related 2',3'-dideoxynucleosidesJ. Exp. Med.168(3),1111-1125(1988)
