Emtricitabine
Cat. No.：YN250721
CAS No. ：143491-57-0
| 产品名称: | Emtricitabine |
| CAS No.: | 143491-57-0 |
| Chemical Name: | 4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone |
| Synonyms: | 恩曲他滨; BW1592 |
| 分子量: | 247.25 |
| 分子式: | C₈H₁₀FN₃O₃S |
| SMILES: | O=C1N=C(N)C(F)=CN1[C@@H]2CS[C@H](CO)O2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Emtricitabine是核苷逆转录酶抑制剂 (NRTI)， 在PBMC细胞中的EC50值为0.01 µM。它可用于HIV感染的研究。 |
| IC50和靶点: | |
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Nelson, M., and Schiavone, M.Emtricitabine (FTC) for the treatment of HIV infectionInt. J. Clin. Pract.58(5),504-510(2004)
Darque, A., Valette, G., Rousseau, F., et al.Quantitation of intracellular triphosphate of emtricitabine in peripheral blood mononuclear cells from human immunodeficiency virus-infected patientsAntimicrob. Agents Chemother.43(9),2245-2250(1999)
Seignères, B., Martin, P., Werle, B., et al.Effects of pyrimidine and purine analog combinations in the duck hepatitis B virus infection modelAntimicrob. Agents Chemother.47(6),1842-1852(2003)
Korba, B.E., Schinazi, R.F., Cote, P., et al.Effect of oral administration of emtricitabine on woodchuck hepatitis virus replication in chronically infected woodchucksAntimicrob. Agents Chemother.44(6),1757-1760(2000)
