Indinavir sulfate
Cat. No.：YN372841
| 产品名称: | Indinavir sulfate |
| CAS No.: | 157810-81-6 |
| Chemical Name: | 2,3,5-trideoxy-N-[(1S,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl]-5-[(2S)-2-[[(1,1-dimethylethyl)amino]carbonyl]-4-(3-pyridinylmethyl)-1-piperazinyl]-2-(phenylmethyl)-D-erythro-pentonamide, monosulfate |
| Synonyms: | 硫酸茚地那韦; MK-639 sulfate; L735524 sulfate |
| 分子量: | 711.87 |
| 分子式: | C₃₆H₄₉N₅O₈S |
| SMILES: | O=C([C@@H](C[C@H](O)CN(CCN(CC1=CN=CC=C1)C2)[C@@H]2C(NC(C)(C)C)=O)CC3=CC=CC=C3)N[C@H]4C(C=CC=C5)=C5C[C@H]4O.O=S(O)(O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Indinavir(MK-639; L735524)硫酸盐是HIV蛋白酶抑制剂，具有很好的口服生物相容性。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Vacca, J.P., Dorsey, B.D., Schleif, W.A., et al.L-735,524: An orally bioavailable human immunodeficiency virus type 1 protease inhibitorProc. Natl. Acad. Sci. USA91(9),4096-4100(1994)
Dorsey, B.D., McDonough, C., McDaniel, S.L., et al.Identification of MK-944a: A second clinical candidate from the hydroxylaminepentanamide isostere series of HIV protease inhibitorsJ. Med. Chem.43(18),3386-3399(2000)
