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Nizatidine

Cat. No.:YN321449

  • CAS No. :76963-41-2

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    • 产品名称: Nizatidine
      CAS No.: 76963-41-2
      Chemical Name: N'-[2-[[[2-[(dimethylamino)methyl]-4-thiazolyl]methyl]thio]ethyl]-N-methyl-2-nitro-1,1-ethenediamine
      Synonyms:尼扎替丁
      分子量:331.46
      分子式:C₁₂H₂₁N₅O₂S₂
      SMILES:CN/C(NCCSCC1=CSC(CN(C)C)=N1)=C\[N+]([O-])=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Nizatidine 是一种口服有效的组胺 H2 受体 (histamine H2receptor) 拮抗剂,可用于胃溃疡的研究。在动物实验中,Nizatidine 的作用是减少胃酸的含量,并防止溃疡愈合后的复发。
      IC50和靶点:
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      Solvent & Solubility:
    • Lin, T.M., Evans, D.C., Warrick, M.W., et al.Actions of nizatidine, a selective histamine H2-receptor antagonist, on gastric acid secretion in dogs, rats and frogsJ. Pharmacol. Exp. Ther.239(2),406-410(1986)

      Feldman, M., and Burton, M.E.Histamine2-receptor antagonists. Standard therapy for acid-peptic diseases. (First of two parts)N. Engl. J. Med.323(24),1672-1680(1990)

      Tuskey, A., and Peura, D.The use of H2 antagonists in treating and preventing NSAID-induced mucosal damageArthritis Res. Ther.15(Suppl 3),1-7(2013)

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