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3-Deazaneplanocin A hydrochloride

Cat. No.：120964-45-6

  • CAS No. ：120964-45-6

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    • 产品名称: 3-Deazaneplanocin A hydrochloride
      CAS No.: 120964-45-6
      Chemical Name:
      Synonyms:3-去氮腺嘌呤A盐酸盐; DZNep hydrochloride; NSC 617989 hydrochloride; 3-Deazaneplanocin hydrochloride
      分子量:298.73
      分子式:C₁₂H₁₅ClN₄O₃
      SMILES:O[C@@H]1[C@H](O)C(CO)=C[C@H]1N2C=NC3=C2C=CN=C3N.[H]Cl
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Simon, J.A., and Lange, C.A.Roles of the EZH2 histone methyltransferase in cancer epigeneticsMutat. Res.647(1-2),21-29(2008)', 'Tseng, C.K.H., Marquez, V.E., Fuller, R.W., et al.Synthesis of 3-deazaneplanocin A, a powerful inhibitor of S-adenosylhomocysteine hydrolase with potent and selective in vitro and in vivo antiviral activitiesJ. Med. Chem.32(7),1442-1446(1989)', 'Fiskus, W., Wang, Y., Sreekumar, A., et al.Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A and the histone deacetylase inhibitor panobinostat against human AML cellsBlood114(13),2733-2743(2009)', 'Bissinger, E.M., Heinke, R., Sippl, W., et al.Targeting epigenetic modifiers: Inhibitors of histone methyltransferasesMed. Chem. Commun.1(2),(2010)
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