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Pinometostat

Cat. No.：1380288-87-8

  • CAS No. ：1380288-87-8

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    • 产品名称: Pinometostat
      CAS No.: 1380288-87-8
      Chemical Name:
      Synonyms:EPZ-5676
      分子量:562.71
      分子式:C₃₀H₄₂N₈O₃
      SMILES:NC1=NC=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](CN([C@@H]4C[C@H](CCC5=NC6=C(C=CC(C(C)(C)C)=C6)N5)C4)C(C)C)O3
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 0.98
    • Nguyen, A.T., He, J., Taranova, O., et al.Essential role of DOT1L in maintaining normal adult hematopoiesisCell Res.21(9),1370-1373(2011)', 'Bernt, K.M., and Armstrong, S.A.A role for DOT1L in MLL-rearranged leukemiasEpigenomics3(6),667-670(2011)', 'Daigle, S.R., Olhava, E.J., Therkelsen, C.A., et al.Potent inhibition of DOT1L as treatment of MLL-fusion leukemiaBlood122(6),1017-1025(2013)', 'Basavapathruni, A., Olhava, E.J., Daigle, S.R., et al.Nonclinical pharmacokinetics and metabolism of EPZ-5676, a novel DOT1L histone methyltransferase inhibitorBiopharm. Drug Dispos.35(4),237-252(2014)
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