NVP-AEW541
Cat. No.：YN440405
CAS No. ：475489-16-8
规格
价格(RMB)
库存
| 产品名称: | NVP-AEW541 |
| CAS No.: | 475489-16-8 |
| Chemical Name: | 7-[cis-3-(1-azetidinylmethyl)cyclobutyl]-5-[3-(phenylmethoxy)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine |
| Synonyms: | AEW541 |
| 分子量: | 439.55 |
| 分子式: | C₂₇H₂₉N₅O |
| SMILES: | NC1=C2C(N([C@@H]3C[C@@H](C3)CN4CCC4)C=C2C5=CC=CC(OCC6=CC=CC=C6)=C5)=NC=N1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | NVP-AEW541 是一种有效的IGF-1R抑制剂，IC50为 0.15 μM，也抑制InsR，IC50为 0.14 μM。 |
| IC50和靶点: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
García-Echeverría, C., Pearson, M.A., Marti, A., et al.In vivo antitumor activity of NVP-AEW541—a novel, potent, and selective inhibitor of the IGF-IR kinaseCancer Cell5(3),231-239(2004)
