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> 产品中心 > 抑制剂 & 激动剂 > MAPK/ERK Pathway > KLF

ML264

Cat. No.:YN350205

  • CAS No. :1550008-55-3

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    • 生物活性
    • 参考文献
    • 产品名称: ML264
      CAS No.: 1550008-55-3
      Chemical Name: (2E)-3-(3-chlorophenyl)-N-[2-[methyl(tetrahydro-1,1-dioxido-2H-thiopyran-4-yl)amino]-2-oxoethyl]-2-propenamide
      Synonyms:CID-51003603
      分子量:384.88
      分子式:C₁₇H₂₁ClN₂O₄S
      SMILES:O=C(NCC(N(C)C(CC1)CCS1(=O)=O)=O)/C=C/C2=CC=CC(Cl)=C2
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: ML264 是一种抗肿瘤剂,可有效和选择性地抑制 Krüppel 样因子 5 (KLF5) 表达。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Bialkowska, A., Crisp, M., Maddoux, F., et al.ML264: An antitumor agent that potently and selectively inhibits krüppel-like factor five (KLF5) expression: A probe for studying colon cancer development and progressionProbe Reports from the NIH Molecular Libraries Program,(2011)

      de Sabando, A.R., Wang, C., He, Y., et al.ML264, a novel small-molecule compound that potently inhibits growth of colorectal cancerMol. Cancer Ther.15(1),72-83(2016)

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    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
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