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> 产品中心 > 抑制剂 & 激动剂 > MAPK/ERK Pathway > MAPKAPK2 (MK2)

CMPD1

Cat. No.:YN350058

  • CAS No. :41179-33-3

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    • 生物活性
    • 参考文献
    • 产品名称: CMPD1
      CAS No.: 41179-33-3
      Chemical Name: 2'-fluoro-N-(4-hydroxyphenyl)-[1,1'-biphenyl]-4-butanamide
      Synonyms:CMPD 1;CMPD1
      分子量:349.40
      分子式:C₂₂H₂₀FNO₂
      SMILES:O=C(NC1=CC=C(O)C=C1)CCCC2=CC=C(C3=CC=CC=C3F)C=C2
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: CMPD1 是一种选择性且非 ATP 竞争性的 p38 MAPK 介导的MK2磷酸化抑制剂,表观Ki(Kiapp)值为 330 nM。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Davidson, W., Frego, L., Peet, G.W., et al.Discovery and characterization of a substrate selective p38α inhibitorBiochemistry43(37),11658-11671(2004)

      Brennan, P.E.Deciphering the true antiproliferative target of an MK2 activation inhibitor in glioblastomaCell Death Dis.e2069,(2016)

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    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
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