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SP-141

Cat. No.：1253491-42-7

  • CAS No. ：1253491-42-7

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    • 产品名称: SP-141
      CAS No.: 1253491-42-7
      Chemical Name:
      Synonyms:SP 141
      分子量:324.38
      分子式:C₂₂H₁₆N₂O
      SMILES:COC1=CC2=C(NC3=C2C=CN=C3C4=C5C=CC=CC5=CC=C4)C=C1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Vassilev, L.T., Vu, B.T., Graves, B., et al.In vivo activation of the p53 pathway by small-molecule antagonists of MDM2Science303(5659),844-848(2004)', 'Wang, W., Qin, J.J., Voruganti, S., et al.The pyrido[b]indole MDM2 inhibitor SP-141 exerts potent therapeutic effects in breast cancer modelsNat. Commun.5,1-12(2014)', 'Wang, W., Qin, J.J., Voruganti, S., et al.Identification of a new class of MDM2 inhibitor that inhibits growth of orthotopic pancreatic tumors in miceGastroenterology147(4),893-902(2014)', 'Nag, S., Qin, J.J., Voruganti, S., et al.Development and validation of a rapid HPLC method for quantitation of SP-141, a novel pyrido[b]indole anticancer agent, and an initial pharmacokinetic study in miceBiomed. Chromatogr.29(5),654-663(2015)
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