MELK-8a hydrochloride
Cat. No.:YN420008
| 产品名称: | MELK-8a hydrochloride |
| CAS No.: | 2096992-20-8 |
| Chemical Name: | 1-methyl-4-[4-[4-[3-(4-piperidinylmethoxy)-4-pyridinyl]-1H-pyrazol-1-yl]phenyl]-piperazine, monohydrochloride |
| Synonyms: | MELK-8a HCl; MELK-8a HCl; MELK-8a HCl; MELK-8a hydrochloride |
| 分子量: | 469.02 |
| 分子式: | C₂₅H₃₃ClN₆O |
| SMILES: | CN(CC1)CCN1C2=CC=C(N3C=C(C4=CC=NC=C4OCC5CCNCC5)C=N3)C=C2.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | MELK-8a hydrochloride是一种新颖的母体胚胎亮氨酸拉链激酶(MELK)抑制剂,其IC50值为2 nM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Touré, B.B., Giraldes, J., Smith, T., et al.Toward the validation of maternal embryonic leucine zipper kinase: Discovery, optimization of highly potent and selective inhibitors, and preliminary biology insightJ. Med. Chem.59(10),4711-4723(2016)