GSK-LSD1 dihydrochloride
Cat. No.:YN380008
| 产品名称: | GSK-LSD1 dihydrochloride |
| CAS No.: | 2102933-95-7 |
| Chemical Name: | rel-N-[(1R,2S)-2-phenylcyclopropyl]-4-piperidinamine, dihydrochloride |
| Synonyms: | GSK-LSD1 2HCl |
| 分子量: | 289.24 |
| 分子式: | C₁₄H₂₂Cl₂N₂ |
| SMILES: | C1(N[C@H]2[C@H](C3=CC=CC=C3)C2)CCNCC1.Cl.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | GSK-LSD1 dihydrochloride 是有效,选择性,不可逆的赖氨酸特异性脱甲基酶 (LSD1) 抑制剂,IC50值为 16 nM。 |
| IC50和靶点: | |
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Shi, Y., Lan, F., Matson, C., et al.Histone demethylation mediated by the nuclear amine oxidase homolog LSD1Cell119(7),941-953(2004)
Forneris, F., Binda, C., Vanoni, M.A., et al.Human histone demethylase LSD1 reads the histone codeJ. Biol. Chem.280(50),41360-41365(2005)
Huang, J., Sengupta, R., Espejo, A.B., et al.p53 is regulated by the lysine demethylase LSD1Nature449,105-108(2007)
Epigenetics probes collection,(2014)