Isatin
Cat. No.：YN380317
| 产品名称: | Isatin |
| CAS No.: | 91-56-5 |
| Chemical Name: | Indole-2,3-dione; 2,3-Dihydro-1H-indole-2,3-dione; 2,3-Dihydroindole-2,3-dione; 2,3-Diketoindoline; 2,3-Dioxo-2,3-dihydroindole; 2,3-Dioxoindoline; 2,3-Indolindione; 2,3-Indolinedione; Isatic Acid Lactam; Isatin; Isatine; Isatinic Acid Anhydride; NSC 9262 |
| Synonyms: | Indoline-2,3-dione |
| 分子量: | 147.13 |
| 分子式: | C₈H₅NO₂ |
| SMILES: | O=C1NC2=C(C=CC=C2)C1=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Isatin (Indoline-2,3-dione) 是单胺氧化酶 (MAO)的有效抑制剂，IC50为3 μM。 也与中枢苯二氮卓受体结合 (对抗氯硝西泮IC50=123 μM)。 还充当心房钠尿肽刺激和一氧化氮刺激的鸟苷酸环化酶拮抗剂。 对5-羟色胺系统有影响。 |
| IC50和靶点: | |
| In Vitro: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
Khalafi-Nezhad, A. et al.: ACS Comb. Sci., 15, 512 (2013)
Li, S. et al.: Eur. J. Med. Chem., 64, 62 (2013)
see Chem. and Eng. News p. 31 May18, 2015
