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Isocarboxazid

Cat. No.:YN380086

  • CAS No. :59-63-2

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    • 产品名称: Isocarboxazid
      CAS No.: 59-63-2
      Chemical Name: 5-methyl-3-isoxazolecarboxylic acid, 2-(phenylmethyl)hydrazide
      Synonyms:异卡波肼
      分子量:231.25
      分子式:C₁₂H₁₃N₃O₂
      SMILES:O=C(C1=NOC(C)=C1)NNCC2=CC=CC=C2
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Isocarboxazid 是一种非选择性的、不可逆的单胺氧化酶monoamine oxidase抑制剂,其在大鼠大脑中测得的IC50值为4.8 μM。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Maxwell, D.R., Gray, W.R., and Taylor, E.M.Relative activity of some inhibitors of mono-amine oxidase in potentiating the action of tryptamine in vitro and in vivoBr. J. Pharmacol. Chemother.17(3),310-320(1961)

      Stanton, H.C., Bowman, Z., and Cooper, C.M.Effects of monoamine oxidase inhibitors on isoproterenol-induced cardiomegaly in ratsToxicol. Appl. Pharmacol.16(1),256-263(1970)

      Yokoyama, T., Kamioka, T., Iwata, N., et al.Effects of RS-2232, a potential antidepressant, on the levels of monoamines, precursor amino acids and their related metabolites in mouse brainJpn. J. Pharmacol.44(4),413-420(1987)

      Barbui, C., Cipriani, A., Patel, V., et al.Efficacy of antidepressants and benzodiazepines in minor depression: Systematic review and meta-analysisBr. J. Psychiatry198(1),11-16(2011)

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