10058-F4

Cat. No.：403811-55-2

CAS No. ：403811-55-2

产品名称:	10058-F4
CAS No.:	403811-55-2
Chemical Name:
Synonyms:	c-Myc Inhibitor
分子量:	249.35
分子式:	C₁₂H₁₁NOS₂
SMILES:	O=C1NC(S/C1=C/C2=CC=C(CC)C=C2)=S
存储:	Please store the product under the recommended conditions in theCertificate of Analysis.
运输:	Room temperature in continental US; may vary elsewhere.

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Purity: 0.98

Yin, X., Giap, C., Lazo, J.S., et al.Low molecular weight inhibitors of Myc-Max interaction and functionOncogene22(40),6151-6159(2003)', 'Huang, M.J., Cheng, Y.C., Liu, C.R., et al.A small-molecule c-Myc inhibitor, 10058-F4, induces cell-cycle arrest, apoptosis, and myeloid differentiation of human acute myeloid leukemiaExp. Hematol.34(11),1480-1489(2006)', 'Guo, J., Parise, R.A., Joseph, E., et al.Efficacy, pharmacokinetics, tissue distribution, and metabolism of the Myc-Max disruptor, 10058-F4 [Z,E]-5-[4-ethylbenzylidine]-2-thioxothiazolidin-4-one, in miceCancer Chemother. Pharmacol.63(4),615-625(2009)', 'Zirath, H., Frenzel, A., Oliynyk, G., et al.MYC inhibition induces metabolic changes leading to accumulation of lipid droplets in tumor cellsProc. Natl. Acad. Sci. USA110(25),10258-10263(2013)', 'Zhang, P., Metukuri, M.R., Bindom, S.M., et al.c-Myc is required for the ChREBP-dependent activation of glucose-responsive genesMol. Endocrinol.24(6),1274-1286(2010)