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Furosemide

Cat. No.:YN360741

  • CAS No. :54-31-9

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    • 参考文献
    • 产品名称: Furosemide
      CAS No.: 54-31-9
      Chemical Name: 5-(aminosulfonyl)-4-chloro-2-[(2-furanylmethyl)amino]-benzoic acid
      Synonyms:呋塞米
      分子量:330.74
      分子式:C₁₂H₁₁ClN₂O₅S
      SMILES:O=C(O)C1=CC(S(=O)(N)=O)=C(Cl)C=C1NCC2=CC=CO2
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Furosemide 是Na+/K+/2Cl-(NKCC),NKCC1 和 NKCC2 共转运蛋白的有效的和具有口服活性抑制剂。Furosemide 也是 GABAA受体拮抗剂,对含 α6 受体的选择性是含 α1 受体的 100 倍。Furosemide 用作利尿试剂,用于充血性心力衰竭,高血压和水肿的研究。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Cadwallader, A.B., de la Torre, X., Tieri, A., et al.The abuse of diuretics as performance-enhancing drugs and masking agents in sport doping: Pharmacology, toxicology and analysisBr. J. Pharmacol.161(1),1-16(2010)

      Cohen, N.D., Peck, K.E., Smith, S.A., et al.Values of urine specific gravity for thoroughbred horses treated with furosemide prior to racing compared with untreated horsesJ. Vet. Diagn. Invest.14(3),231-235(2002)

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