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ON123300

Cat. No.：1357470-29-1

  • CAS No. ：1357470-29-1

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    • 产品名称: ON123300
      CAS No.: 1357470-29-1
      Chemical Name:
      Synonyms:ON 123300,ON-123300，ON123300
      分子量:429.52
      分子式:C₂₄H₂₇N₇O
      SMILES:N#CC1=CC2=CN=C(NC3=CC=C(N4CCN(C)CC4)C=C3)N=C2N(C5CCCC5)C1=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Zhang, X., Lv, H., Zhou, Q., et al.Preclinical pharmacological evaluation of a novel multiple kinase inhibitor, ON123300, in brain tumor modelsMol. Cancer Ther.13(5),1105-1116(2014)', 'Reddy, M.V.R., Akula, B., Conseza, S.C., et al.Discovery of 8-cyclopentyl-2-[4-(4-methyl-piperazin-1-yl)-phenylamino]-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carbonitrile (7x) as a potent inhibitor of cyclin-dependent kinase 4 (CDK4) and AMPK-related kinase 5 (ARK5)J. Med. Chem.57(3),578-599(2014)
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