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GSK461364

Cat. No.：929095-18-1

  • CAS No. ：929095-18-1

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    • 产品名称: GSK461364
      CAS No.: 929095-18-1
      Chemical Name:
      Synonyms:GSK461364A
      分子量:543.60
      分子式:C₂₇H₂₈F₃N₅O₂S
      SMILES:O=C(C(SC(N1C=NC2=CC=C(C=C12)CN3CCN(CC3)C)=C4)=C4O[C@@H](C5=CC=CC=C5C(F)(F)F)C)N
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Schöffski, P.Polo-like kinase (PLK) inhibitors in preclinical and early clinical development in oncologyOncologist14(6),559-570(2009)', 'Gilmartin, A.G., Bleam, M.R., Richter, M.C., et al.Distinct concentration-dependent effects of the polo-like kinase 1-specific inhibitor GSK461364A, including differential effect on apoptosisCancer Res.69(17),6969-6977(2009)', 'Degenhardt, Y., Greshock, J., Laquerre, S., et al.Sensitivity of cancer cells to Plk1 inhibitor GSK461364A is associated with loss of p53 function and chromosome instabilityMol. Cancer Ther.9(7),2079-2089(2010)', 'Danovi, D., Folarin, A., Gogolok, S., et al.A high-content small molecule screen identifies sensitivity of glioblastoma stem cells to inhibition of polo-like kinase 1PLoS One8(10),1-13(2013)
    • 摩尔计算器
    • 稀释计算器
    摩尔浓度计算器方程 :
    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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    质量 浓度 体积 分子量
    稀释计算器 :
    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
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