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> 产品中心 > 抑制剂 & 激动剂 > Cell Cycle > Polo-like Kinase (PLK)

AK-1

Cat. No.:330461-64-8

  • CAS No. :330461-64-8

    • 产品资料
    • 参考文献
    • 产品名称: AK-1
      CAS No.: 330461-64-8
      Chemical Name:
      Synonyms:AK-1,AK1,AK 1
      分子量:403.45
      分子式:C₁₉H₂₁N₃O₅S
      SMILES:O=C(NC1=CC=CC([N+]([O-])=O)=C1)C2=CC=CC(S(=O)(N3CCCCCC3)=O)=C2
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 0.98
    • Taylor, D.M., Balabadra, U., Xiang, Z., et al.A brain-permeable small molecule reduces neuronal cholesterol by inhibiting activity of sirtuin 2 deacetylaseACS Chem Biol.6(6),540-546(2011)', "Outeiro, T.F., Kontopoulos, E., Altmann, S.M., et al.Sirtuin 2 inhibitors rescue α-synuclein-mediated toxicity in models of Parkinson's diseaseScience317(5837),516-519(2007)", 'Lee, S.D., Kim, W., Jeong, J.-W., et al.AK-1, a SIRT2 inhibitor, destabilizes HIF-1α and diminishes its transcriptional activity during hypoxiaCancer Lett.373(1),138-145(2016)', 'Luthi-Carter, R., Taylor, D.M., Pallos, J., et al.SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesisProc. Natl. Acad. Sci. USA107(17),7927-7932(2010)
    • 摩尔计算器
    • 稀释计算器
    摩尔浓度计算器方程 :
    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    计算

    质量 浓度 体积 分子量
    稀释计算器 :
    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
    • C1
      V1
      C2
      V2


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