BETd-260
Cat. No.：YN430005
CAS No. ：2093388-62-4
规格
价格(RMB)
库存
| 产品名称: | BETd-260 |
| CAS No.: | 2093388-62-4 |
| Chemical Name: | |
| Synonyms: | ZBC 260 |
| 分子量: | 798.89 |
| 分子式: | C₄₃H₄₆N₁₀O₆ |
| SMILES: | CCN1N=C(C2CC2)C=C1NC3=NC(C(NCCCCCC4=CC=CC5=C4CN(C6C(NC(CC6)=O)=O)C5=O)=O)=NC7=C3C8=CC(OC)=C(C9=C(C)ON=C9C)C=C8N7 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | BETd-260 (ZBC 260) 是一种有效的PROTAC BET降解剂，在白血病细胞 RS4;11 中，在 30 pM 的低浓度下，能够降低BRD4蛋白活性。BETd-260 能显著抑制肝细胞癌 HCC 细胞的活性并诱导细胞凋亡 (apoptosis)。 |
| IC50和靶点: | [{name:"BRD4:<30 pM (IC50)"},{name: "BRD2:30-100 pM (IC50)"},{name: "BRD3:30-100 pM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
