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Obatoclax Mesylate

Cat. No.：803712-79-0

  • CAS No. ：803712-79-0

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    • 产品名称: Obatoclax Mesylate
      CAS No.: 803712-79-0
      Chemical Name:
      Synonyms:GX15-070 Mesylate
      分子量:413.49
      分子式:C₂₁H₂₃N₃O₄S
      SMILES:COC1=CC(C2=CC3=C(C=CC=C3)N2)=N/C1=C\C4=C(C=C(N4)C)C.CS(=O)(O)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Shore, G.C., and Viallet, J.Modulating the Bcl-2 family of apoptosis suppressors for potential therapeutic benefit in cancerHematology Am. Soc. Hematol. Educ. Program,226-230(2005)', 'Konopleva, M., Watt, J., Contractor, R., et al.Mechanisms of antileukemic activity of the novel Bcl-2 homology domain-3 mimetic GX15-070 (obatoclax)Cancer Res.68(9),3413-3420(2008)', 'Trudel, S., Li, Z.H., Rauw, J., et al.Preclinical studies of the pan-Bcl inhibitor obatoclax (GX015-070) in multiple myelomaBlood109(12),5430-5438(2007)', 'Andreu-Fernández, V., Genovés, A., Messeguer, A., et al.BH3-mimetics- and cisplatin-induced cell death proceeds through different pathways depending on the availability of death-related cellular componentsPLoS One8(2),e56881(2013)
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