NSC5844
Cat. No.:YN250004
CAS No. :140926-75-6
产品名称: | NSC5844 |
CAS No.: | 140926-75-6 |
Chemical Name: | N1,N2-bis(7-chloro-4-quinolinyl)-1,2-ethanediamine |
Synonyms: | RE-640 |
分子量: | 383.27 |
分子式: | C₂₀H₁₆Cl₂N₄ |
SMILES: | ClC1=CC=C2C(NCCNC3=CC=NC4=CC(Cl)=CC=C34)=CC=NC2=C1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | NSC5844 是 4-氨基喹啉衍生物,具有抗肿瘤和抗疟疾活性。 |
IC50和靶点: | |
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Vennerstrom, J.L., Ellis, W.Y., Ager, A.L., Jr., et al.Bisquinolines. 1. N,N-bis(7-chloroquinolin-4-yl)alkanediamines with potential against chloroquine-resistant malariaJ. Med. Chem.35(11),2129-2134(1992)
Zhang, H., Solomon, V.R., Hu, C., et al.Synthesis and in vitro cytotoxicity evaluation of 4-aminoquinoline derivativesBiomed. Pharmacother.62(2),65-69(2008)
Burnett, J.C., Schmidt, J.J., Stafford, R.G., et al.Novel small molecule inhibitors of botulinum neurotoxin A metalloprotease activityBiochem. Biophys. Res. Commun.310(1),84-93(2003)