Ivermectin B1b
Cat. No.：YN250369
CAS No. ：70209-81-3
| 产品名称: | Ivermectin B1b |
| CAS No.: | 70209-81-3 |
| Chemical Name: | 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-avermectin A1a |
| Synonyms: | |
| 分子量: | 861.07 |
| 分子式: | C₄₇H₇₂O₁₄ |
| SMILES: | CC([C@H]1O[C@]2(CC[C@@H]1C)C[C@](O3)([H])C[C@](C/C=C([C@H]([C@H](/C=C/C=C4[C@@]5(O)[C@](C=C(C)[C@@H](O)[C@@]5([H])OC/4)([H])C3=O)C)O[C@@]6([H])C[C@@H]([C@@H](O[C@@]7([H])C[C@@H]([C@@H](O)[C@H](C)O7)OC)[C@H](C)O6)OC)\C)([H])O2)C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ivermectin B1b 是 Ivermectin 的次要成分。Ivermectin 是一种有效的抗寄生虫药物，可抑制 SARS-CoV-2 复制。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Campbell, W.C., Fisher, M.H., Stapley, E.O., et al.Ivermectin: A potent new antiparasitic agentScience221(4613),823-828(1983)
Wolsetnholme, A.J., and Rogers, A.T.Glutamate-gated chloride channels and the mode of action of the avermectin/milbemycin anthelminticsParasitology131(Suppl),S85-S95(2005)
Arena, J.P., Liu, K.K., Paress, P.S., et al.The mechanism of action of avermectins in Caenorhabditis elegans: Correlation between activation of glutamate-sensitive chloride current, membrane binding, and biological activityJ. Parasitol.81(2),286-294(1995)
Caly, L., Druce, J.D., Catton, M.G., et al.The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitroAntiviral Res.178:104787,(2020)
