Pyronaridine tetraphosphate
Cat. No.：YN250594
CAS No. ：76748-86-2
| 产品名称: | Pyronaridine tetraphosphate |
| CAS No.: | 76748-86-2 |
| Chemical Name: | 4-[(7-chloro-2-methoxybenzo[b]-1,5-naphthyridin-10-yl)amino]-2,6-bis(1-pyrrolidinylmethyl)-phenol, tetraphosphate |
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| 分子量: | 910.03 |
| 分子式: | C₂₉H₄₄ClN₅O₁₈P₄ |
| SMILES: | OC1=C(CN2CCCC2)C=C(NC3=C4N=C(OC)C=CC4=NC5=CC(Cl)=CC=C53)C=C1CN6CCCC6.O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Pyronaridine tetraphosphate 是一种含甘露醇的抗疟疾药物，对耐药的镰状疟原虫，间日疟原虫， 卵形疟原虫和三日疟原虫均具有良好的疗效。 |
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Vivas, L., Rattray, L., Stewart, L., et al.Anti-malarial efficacy of pyronaridine and artesunate in combination in vitro and in vivoActa Trop.105(3),222-228(2008)
Puhl, A.C., Fritch, E.J., Lane, T.R., et al.Repurposing the ebola and marburg virus inhibitors tilorone, quinacrine, and pyronaridine: In vitro activity against SARS-CoV-2 and potential mechanismsACS Omega6(11),7454-7468(2021)
Villanueva, P.J., Martinez, A., Baca, S.T., et al.Pyronaridine exerts potent cytotoxicity on human breast and hematological cancer cells through induction of apoptosisPLoS One13(11),e0206467(2018)
