Avermectin B1a
Cat. No.：YN250631
CAS No. ：65195-55-3
| 产品名称: | Avermectin B1a |
| CAS No.: | 65195-55-3 |
| Chemical Name: | 5-O-demethyl-avermectin A1a |
| Synonyms: | Abamectin B1a |
| 分子量: | 873.08 |
| 分子式: | C₄₈H₇₂O₁₄ |
| SMILES: | C[C@@H](CC)[C@]1([H])[C@@H](C)C=C[C@@]2(O[C@@]3([H])C[C@]([H])(OC([C@@]4([H])[C@@](/C(CO5)=C/C=C/[C@H](C)[C@H](O[C@@]6([H])C[C@H](OC)[C@@H](O[C@]7([H])O[C@@H](C)[C@H](O)[C@@H](OC)C7)[C@H](C)O6)/C(C)=C/C3)(O)[C@@]5([H])[C@H](O)C(C)=C4)=O)C2)O1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Avermectin B1a 是一种抗寄生虫剂，能够使线虫瘫痪。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Yamamuro, D., Uchida, R., Takahashi, Y., et al.Screening for microbial metabolites affecting phenotype of Caenorhabditis elegansBiol. Pharm. Bull.34(10),1619-1623(2011)
Wang, C.C., and Pong, S.S.Actions of avermectin B1a on GABA nervesProg. Clin. Biol. Res.97,373-395(1982)
Huang, J., and Casida, J.E.Avermectin B1a binds to high- and low-affinity sites with dual effects on the g-aminobutyric acid-gated chloride channel of cultured cerebellar granule neuronsJ. Pharm. Exp. Ther.281(1),261-266(1997)
Graham, D., Pfeiffer, F., and Betz, H.Avermectin B1a inhibits the binding of strychnine to the glycine receptor of rat spinal cordNeurosci. Lett.29(2),173-176(1982)
Wescott, R.B., Farrell, C.J., Gallina, A.M., et al.Efficacy of avermectin B1a for treatment of experimentally induced nematode infections in cattleAm. J. Vet. Res.41(8),1326-1328(1980)
Todd, K.S., Jr., Mansfield, M.E., and DiPietro, J.A.Anthelmintic efficacy of avermectin B1a and dihydroavermectin B1a against ovine gastrointestinal nematodes in 1977Am. J. Vet. Res.45(5),976-977(1984)
