Flubendazole
Cat. No.：YN250988
CAS No. ：31430-15-6
| 产品名称: | Flubendazole |
| CAS No.: | 31430-15-6 |
| Chemical Name: | N-[6-(4-fluorobenzoyl)-1H-benzimidazol-2-yl]-carbamic acid, methyl ester |
| Synonyms: | 氟苯咪唑 |
| 分子量: | 313.28 |
| 分子式: | C₁₆H₁₂FN₃O₃ |
| SMILES: | O=C(OC)NC1=NC2=CC=C(C(C3=CC=C(F)C=C3)=O)C=C2N1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Flubendazole 是一种安全有效的驱虫药物，广泛应用于人类、啮齿动物和反刍动物的驱虫。Flubendazole 通过抑制微管功能等机制发挥抗癌作用。Flubendazole 诱导p53介导的细胞凋亡，抑制 G2/M 细胞周期。 |
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Čáňová, K., Rozkydalová, L., and Rudolf, E.Anthelmintic flubendazole and its potential use in anticancer therapyActa Medica (Hradec Kralove)60(1),5-11(2017)
Maki, J., and Yanagisawa, T.A comparison of the effects of flubendazole and thiabendazole on the larvae of Angiostrongylus cantonensis, Trichinella spiralis, Diphyllobothrium erinacei and Hymenolepis nana in miceParasitology87(Pt 3),525-531(1983)
Lacey, E.Mode of action of benzimidazolesParasitol. Today6(4),112-115(1990)
Hou, Z.-J., Lou, X., Zhang, W., et al.Flubendazole, FDA-approved anthelmintic, targets breast cancer stem-like cellsOncotarget6(8),6326-6340(2015)
