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Triclabendazole

Cat. No.:YN251111

  • CAS No. :68786-66-3

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Triclabendazole
      CAS No.: 68786-66-3
      Chemical Name: 6-chloro-5-(2,3-dichlorophenoxy)-2-(methylthio)-1H-benzimidazole
      Synonyms:三氯苯达唑; CGA89317
      分子量:359.66
      分子式:C₁₄H₉Cl₃N₂OS
      SMILES:CSC1=NC2=CC(OC3=CC=CC(Cl)=C3Cl)=C(Cl)C=C2N1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Triclabendazole(CGA89317)为苯并咪唑,与微管蛋白结合,损害细胞内运输机制,且干扰蛋白质的合成。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Shrifi, Y., Farahnak, A., Golestani, A., et al.Triclabendazole effect on protease enzyme activity in the excretory- secretory products of Fasciola hepatica in vitroIran. J. Parasitol.9(1),107-113(2014)

      Smeal, M.G., and Hall, C.A.The activity of triclabendazole against immature and adult Fasciola hepatica infections in sheepAust. Vet. J.60(11),329-331(1983)

      Lee, Y.J., Burlet, E., Wang, S., et al.Triclabendazole protects yeast and mammalian cells from oxidative stress: Identification of a potential neuroprotective compoundBiochem. Biophys. Res. Commun.414(1),205-208(2011)

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