Artemotil
Cat. No.：YN251129
CAS No. ：75887-54-6
| 产品名称: | Artemotil |
| CAS No.: | 75887-54-6 |
| Chemical Name: | (3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-ethoxydecahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin |
| Synonyms: | 蒿乙醚; β-Arteether; (+)-Arteether; Arteether |
| 分子量: | 312.40 |
| 分子式: | C₁₇H₂₈O₅ |
| SMILES: | C[C@@H]1[C@@](CC[C@@H](C)[C@]2([H])CC[C@]3(C)O4)([H])[C@@]2(OO3)[C@]4([H])O[C@@H]1OCC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Artemotil (β-Arteether) 具有抗疟疾活性，可用于研究耐Plasmodium falciparum的恶性疟原虫疟疾，IC50值为 1.61 nM。Artemotiltil 对大鼠，狗和猴子具有 CNS 神经毒性和厌食毒性。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Brossi, A., Venugopalan, B., Dominguez Gerpe, L., et al.Arteether, a new antimalarial drug: Synthesis and antimalarial propertiesJ. Med. Chem.31(3),645-650(1988)
