Lumefantrine
Cat. No.：YN251135
CAS No. ：82186-77-4
| 产品名称: | Lumefantrine |
| CAS No.: | 82186-77-4 |
| Chemical Name: | (9Z)-2,7-dichloro-9-[(4-chlorophenyl)methylene]-α-[(dibutylamino)methyl]-9H-fluorene-4-methanol |
| Synonyms: | 苯芴醇; Benflumetol |
| 分子量: | 528.94 |
| 分子式: | C₃₀H₃₂Cl₃NO |
| SMILES: | OC(CN(CCCC)CCCC)C1=CC(Cl)=CC(/C2=C\C3=CC=C(Cl)C=C3)=C1C4=C2C=C(Cl)C=C4 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Lumefantrine是一种抗疟疾药物, 与Artemether联用, 作为一线和二线抗疟药。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Pascual, A., Parola, P., Benoit-Vical, F., et al.Ex vivo activity of the ACT new components pyronaridine and piperaquine in comparison with conventional ACT drugs against isolates of Plasmodium falciparumMalar. J.11,(2012)
Askling, H.H., Bruneel, F., Burchard, G., et al.Management of imported malaria in EuropeMalar. J.11,(2012)
Mayxay, M., Khanthavong, M., Chanthongthip, O., et al.Efficacy of artemether-lumefantrine, the nationally-recommended artemisinin combination for the treatment of uncomplicated falciparum malaria, in southern LaosMalar. J.11,184(2012)
Du, L.P., Tsai, K.C., Li, M.Y., et al.The pharmacophore hypotheses of IKr potassium channel blockers: Novel class III antiarrhythmic agentsBioorg. Med. Chem. Lett.14(18),4771-4777(2004)
