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Amprolium hydrochloride

Cat. No.:YN251174

  • CAS No. :137-88-2

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    • 参考文献
    • 产品名称: Amprolium hydrochloride
      CAS No.: 137-88-2
      Chemical Name: 1-[(4-amino-2-propyl-5-pyrimidinyl)methyl]-2-methyl-pyridinium, monochloride, monohydrochloride
      Synonyms:氨丙啉盐酸盐
      分子量:315.24
      分子式:C₁₄H₂₀Cl₂N₄
      SMILES:CC1=CC=CC=[N+]1CC2=CN=C(CCC)N=C2N.[Cl-].Cl
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Amprolium盐酸盐是用于家禽的一种抗球虫药, 是一种类硫胺素, 通过抑制硫胺素吸收和碳水化合物合成而抑制球虫的硫胺转运。
      IC50和靶点:
      In Vitro:
      In Vivo:
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    • James, S.Thiamine uptake in isolated schizonts of Eimeria tenella and the inhibitory effects of amproliumParasitology80(2),313-322(1980)

      Brin, M.The antithiamine effects of amprolium in rats on tissue transketolase activityToxicol. Appl. Pharmacol.6(4),454-458(1964)

      Joyner, L.P., and Norton, C.C.The anticoccidial effects of amprolium, dinitolmide and monensin against Eimeria maxima, E. brunetti and E. acervulina with particular reference to oocyst sporulationParasitology75(2),155-164(1977)

      Abbas, R.I., Manzoor, Z., Munawar, S.H., et al.Anticoccidial activity of hydrochloric acid (HCl) against Eimeria tenella in broiler chickensPesq. Vet. Bras.31(5),425-429(2011)

      Chornyy, S., Parkhomenko, J., and Chorna, N.Thiamine deficiency caused by thiamine antagonists triggers upregulation of apoptosis inducing factor gene expression and leads to caspase 3-mediated apoptosis in neuronally differentiated rat PC-12 cellsActa. Biochim. Pol.54(2),315-322(2007)

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