PRT-060318
Cat. No.：YN440236
CAS No. ：1194961-19-7
规格
价格(RMB)
库存
| 产品名称: | PRT-060318 |
| CAS No.: | 1194961-19-7 |
| Chemical Name: | 2-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[(3-methylphenyl)amino]-5-pyrimidinecarboxamide |
| Synonyms: | PRT318 |
| 分子量: | 340.42 |
| 分子式: | C₁₈H₂₄N₆O |
| SMILES: | O=C(C1=CN=C(N[C@H]2[C@@H](N)CCCC2)N=C1NC3=CC=CC(C)=C3)N |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | PRT-060318 (PRT318)是新颖选择性的酪氨酸激酶 (Syk) 抑制剂，IC50值为4 nM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Woodford, M.R., Dunn, D.M., Blanden, A.R., et al.The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug bindingNat. Commun.7,12037(2016)
Archari, G.A., and Ramesh, R.Characterization of bacteria degrading 3-hydroxy palmitic acid methyl ester (3OH-PAME), a quorum sensing molecule of Ralstonia solanacearumLett. Appl. Microbiol.60(5),447-455(2015)
Hoellenriegel, J., Coffey, G.P., Sinha, U., et al.Selective, novel spleen tyrosine kinase (Syk) inhibitors suppress chronic lymphocytic leukemia B-cell activation and migrationLeukemia26(7),1576-1583(2012)
