Oxymatrine
Cat. No.：YN450141
CAS No. ：16837-52-8
规格
价格(RMB)
库存
| 产品名称: | Oxymatrine |
| CAS No.: | 16837-52-8 |
| Chemical Name: | (4R,7aS,13aR,13bR,13cS)-dodecahydro-4-oxide-1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one |
| Synonyms: | 氧化苦参碱 |
| 分子量: | 264.36 |
| 分子式: | C₁₅H₂₄N₂O₂ |
| SMILES: | O=C1CCC[C@]2([H])[C@@]3([H])CCC[N@@+]4([O-])[C@@]3([H])[C@](CCC4)([H])CN21 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Oxymatrine是来自槐属物种根部的生物碱，具有抗炎，抗纤维化和抗肿瘤的作用。能抑制iNOS表达和TGF-β/Smad通路。Oxymatrine 可抑制博卡病毒MVC复制，降低病毒基因表达并减少病毒感染诱导的细胞凋亡 (apoptosis)。 |
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Ling, Q., Xu, X., Wei, X., et al.Oxymatrine induces human pancreatic cancer PANC-1 cells apoptosis via regulating expression of Bcl-2 and IAP families, and releasing of cytochrome cJ. Exp. Clin. Cancer Res.30,66(2011)
Cui, X., Wang, Y., Kokudo, N., et al.Traditional Chinese medicine and related active compounds against hepatitis B virus infectionBiosci. Trends4(2),39-47(2010)
Ma, Z.J., Li, Q., Wang, J.B., et al.Combining oxymatrine or matrine with lamivudine increased its antireplication effect against the hepatitis B virus in vitroEvid. Based Complement. Alternat. Med.2013,186573(2013)
Chai, N.L., Fu, Q., Shi, H., et al.Oxymatrine liposome attenuates hepatic fibrosis via targeting hepatic stellate cellsWorld J. Gastroenterol.18(31),4199-4206(2012)
Wu, X.L., Zeng, W.Z., Jiang, M.D., et al.Effect of oxymatrine on the TGβSmad signaling pathway in rats with CCl4-induced hepatic fibrosisWorld J. Gastroenterol.14(13),2100-2105(2008)
Guzman, J.R., Koo, J.S., Goldsmith, J.R., et al.Oxymatrine prevents NF-κB nuclear translocation and ameliorates acute intestinal inflammationSci. Rep.3,1629(2013)
