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R-7050

Cat. No.：303997-35-5

  • CAS No. ：303997-35-5

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    • 产品名称: R-7050
      CAS No.: 303997-35-5
      Chemical Name:
      Synonyms:TNF-α Antagonist III
      分子量:380.77
      分子式:C₁₆H₈ClF₃N₄S
      SMILES:FC(F)(C1=NN=C2N1C3=CC(Cl)=CC=C3N=C2SC4=CC=CC=C4)F
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Gururaja, T.L., Yung, S., Ding, R., et al.A class of small molecules that inhibit TNFα-induced survival and death pathways via prevention of interactions between TNFαRI, TRADD, and RIP1Chem. Biol.14(10),1105-1118(2007)', 'King, M.D., Alleyne, C.H., Jr., and Dhandapani, K.M.TNF-alpha receptor antagonist, R-7050, improves neurological outcomes following intracerebral hemorrhage in miceNeurosci. Lett.542,92-96(2013)', 'Wu, W., and Zhang, H.Role of tumor necrosis factor-α and interleukin-1β in anorexia induction following oral exposure to the trichothecene deoxynivalenol (vomitoxin) in the mouseJ. Toxicol. Sci.39(6),875-886(2014)
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