SRPIN340

Cat. No.：218156-96-8

CAS No. ：218156-96-8

产品名称:	SRPIN340
CAS No.:	218156-96-8
Chemical Name:
Synonyms:	SRPK inhibitor
分子量:	349.35
分子式:	C₁₈H₁₈F₃N₃O
SMILES:	O=C(NC1=CC(C(F)(F)F)=CC=C1N2CCCCC2)C3=CC=NC=C3
存储:	Please store the product under the recommended conditions in theCertificate of Analysis.
运输:	Room temperature in continental US; may vary elsewhere.

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Purity: 0.98

Ghosh, G., and Adams, J.A.Phosphorylation mechanism and structure of serine-arginine protein kinasesFEBS J.278(4),587-597(2011)', 'Fukuhara, T., Hosoya, T., Shimizu, S., et al.Utilization of host SR protein kinases and RNA-splicing machinery during viral replicationProc. Natl. Acad. Sci. USA103(30),11329-11333(2006)', 'Karakama, Y., Sakamoto, N., Itsui, Y., et al.Inhibition of hepatitis C virus replication by a specific inhibitor of serine-arginine-rich protein kinaseAntimicrob. Agents Chemother.54(8),3179-3186(2010)', 'Ghadimi, M.P., Lopez, G., Torres, K.E., et al.Targeting the PI3K/mTOR axis, alone and in combination with autophagy blockade, for the treatment of malignant peripheral nerve sheath tumorsMol. Cancer Ther.11(8),1758-1769(2012)', 'Gammons, M.V.R., Dick, A.D., Harper, S.J., et al.SRPK1 inhibition modulates VEGF splicing to reduce pathological neovascularization in a rat model of retinopathy of prematurityInvest. Ophthalmol. Vis. Sci.54(8),5797-5806(2013)', 'Dong, Z., Noda, K., Kanda, A., et al.Specific inhibition of serine/arginine-rich protein kinase attenuates choroidal neovascularizationMol. Vis.19,536-543(2013)