Adavosertib
Cat. No.：YN290093
CAS No. ：955365-80-7
规格
价格(RMB)
库存
| 产品名称: | Adavosertib |
| CAS No.: | 955365-80-7 |
| Chemical Name: | 1,2-dihydro-1-[6-(1-hydroxy-1-methylethyl)-2-pyridinyl]-6-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-2-(2-propen-1-yl)-3H-pyrazolo[3,4-d]pyrimidin-3-one |
| Synonyms: | AZD1775; MK-1775 |
| 分子量: | 500.60 |
| 分子式: | C₂₇H₃₂N₈O₂ |
| SMILES: | O=C1N(N(C2=NC(NC3=CC=C(C=C3)N4CCN(CC4)C)=NC=C21)C5=NC(C(O)(C)C)=CC=C5)CC=C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Adavosertib (AZD-1775; MK-1775) 是一种有效的Wee1抑制剂，IC50值为 5.2 nM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Hirai, H., Iwasawa, Y., Okada, M., et al.Small-molecule inhibition of Wee1 kinase by MK-1775 selectively sensitizes p53-deficient tumor cells to DNA-damaging agentsMol. Cancer Ther.8(11),2992-3000(2009)
