GSK-4716
Cat. No.：YN481707
CAS No. ：101574-65-6
规格
价格(RMB)
库存
| 产品名称: | GSK-4716 |
| CAS No.: | 101574-65-6 |
| Chemical Name: | 4-hydroxy-2-[[4-(1-methylethyl)phenyl]methylene]hydrazide benzoic acid |
| Synonyms: | GSK4716; GSK 4716; GSK-4716. |
| 分子量: | 282.34 |
| 分子式: | C₁₇H₁₈N₂O₂ |
| SMILES: | O=C(N/N=C/C1=CC=C(C(C)C)C=C1)C2=CC=C(O)C=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | GSK-4716 是一种选择性ERRβ/γ激动剂。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Schreiber, S.N., Knutti, D., Brogli, K., et al.The transcriptional coactivator PGC-1 regulates the expression and activity of the orphan nuclear receptor estrogen-related receptor α (ERRα)J. Biol. Chem.278(11),9013-9018(2003)
Wang, L., Zuercher, W.J., Consler, T.G., et al.X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulationJ. Biol. Chem.281(49),37773-37781(2006)
Rangwala, S.M., Wang, X., Calvo, J.A., et al.Estrogen-related receptor γ is a key regulator of muscle mitochondrial activity and oxidative capacityJ. Biol. Chem.285(29),22619-22629(2010)
