BI605906
Cat. No.：YN410039
CAS No. ：960293-88-3
| 产品名称: | BI605906 |
| CAS No.: | 960293-88-3 |
| Chemical Name: | 3-amino-4-(1,1-difluoropropyl)-6-[4-(methylsulfonyl)-1-piperidinyl]-thieno[2,3-b]pyridine-2-carboxamide |
| Synonyms: | BI-605906 |
| 分子量: | 432.51 |
| 分子式: | C₁₇H₂₂F₂N₄O₃S₂ |
| SMILES: | O=C(C1=C(N)C2=C(C(F)(F)CC)C=C(N3CCC(S(=O)(C)=O)CC3)N=C2S1)N |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | BI605906 是一种新型IKKβ抑制剂，在 0.1 mM ATP 条件下测定时IC50值为 380 nM。 |
| IC50和靶点: | [{name:"IKKβ:380 nM (IC50, at 0.1 mM ATP)"}] |
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| Clinical Trial: | |
| Solvent & Solubility: |
Clark, K., Peggie, M., Plater, L., et al.Novel cross-talk within the IKK family controls innate immunityBiochem. J.434(1),93-104(2011)
Cameron, A.R., Morrison, V.L., Levin, D., et al.Anti-inflammatory effects of metformin irrespective of diabetes statusCirc. Res.119(5),652-665(2016)
