Roluperidone
Cat. No.：YN321224
CAS No. ：359625-79-9
| 产品名称: | Roluperidone |
| CAS No.: | 359625-79-9 |
| Chemical Name: | 2-[[1-[2-(4-fluorophenyl)-2-oxoethyl]-4-piperidinyl]methyl]-2,3-dihydro-1H-isoindol-1-one |
| Synonyms: | CYR-101; MIN-101; MT-210 |
| 分子量: | 366.43 |
| 分子式: | C₂₂H₂₃FN₂O₂ |
| SMILES: | O=C1N(CC2CCN(CC(C3=CC=C(F)C=C3)=O)CC2)CC4=C1C=CC=C4 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Roluperidone (CYR-101) 是一种新型环酰胺衍生物，对5-HT2A和sigma-2受体具有高亲和力，Ki分别为 7.53 nM 和 8.19 nM。 |
| IC50和靶点: | [{name:"5-HT2A Receptor:7.53 nM (Ki)"},{name: "Sigma-2 Receptor:8.19 nM (Ki)"}] |
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Davidson, M., Saoud, J., Staner, C., et al.Efficacy and safety of MIN-101: A 12-week randomized, double-blind, placebo-controlled trial of a new drug in development for the treatment of negative symptoms in schizophreniaAm. J. Psychiatry174(12),1195-1202(2017)
