ST1936
Cat. No.：YN322187
CAS No. ：1210-81-7
| 产品名称: | ST1936 |
| CAS No.: | 1210-81-7 |
| Chemical Name: | 5-Chloro-3-[2-(dimethylamino)ethyl]-2-methyl-indole; 5-Chloro-N,N,2-trimethyl-1H-indole-3-ethanamine; N,N-Dimethyl-2-(5-chloro-2-methylindol-3-yl)ethylamine; ST 1936 |
| Synonyms: | |
| 分子量: | 236.74 |
| 分子式: | C13H17ClN2 |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | ST1936是一种选择性的纳摩尔亲和力的5-HT6受体激动剂，对人5-HT6、5-HT7和 5-HT2B受体的Ki值分别为 13 nM，168 nM 和 245 nM。ST1936 对人和大鼠的 α2 肾上腺素受体也显示出中等亲和力 (Ki为 300 nM)。 |
| IC50和靶点: | [{name:"5-HT6 Receptor:13 nM (Ki)"},{name: "5-HT7 Receptor:168 nM (Ki)"},{name: "5-HT2B Receptor:245 nM (Ki)"},{name: "α1-adrenergic receptor:390 nM (Ki, rat)"},{name: "α2-adrenergic receptor:300 nM (Ki, rat)"},{name: "α2-adrenergic receptor:300 nM (Ki, human)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
(1) Scheggi, S., et al.: Behav Brain Res. 224, 35 (2011) & (2) Valentini, V., et al.: Neuropharmacology 60, 602 (2011)
