Itopride hydrochloride
Cat. No.：YN380182
CAS No. ：122892-31-3
| 产品名称: | Itopride hydrochloride |
| CAS No.: | 122892-31-3 |
| Chemical Name: | N-[[4-[2-(dimethylamino)ethoxy]phenyl]methyl]-3,4-dimethoxy-benzamide, monohydrochloride |
| Synonyms: | 盐酸伊托必利; HSR803 |
| 分子量: | 394.89 |
| 分子式: | C₂₀H₂₇ClN₂O₄ |
| SMILES: | O=C(NCC1=CC=C(OCCN(C)C)C=C1)C2=CC=C(OC)C(OC)=C2.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Itopride盐酸盐是乙酰胆碱酯酶（AChE）抑制剂和D2DR抑制剂。 |
| IC50和靶点: | |
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Kawachi, M., Matsunaga, Y., Tanaka, T., et al.Acotiamide hydrochloride (Z-338) enhances gastric motility and emptying by inhibiting acetylcholinesterase activity in ratsEur. J. Pharmacol.666(1-3),218-225(2011)
Butt, A.I., Khan, B.T., Khan, A., et al.Ranitidine can potentiate the prokinetic effect of itopride at low doses- an in vitro studyJ. Ayub Med. Coll. Abbottabad29(4),554-558(2017)
Ito, K., Kawachi, M., Matsunaga, Y., et al.Acotiamide hydrochloride, a therapeutic agent for functional dyspepsia, enhances acetylcholine-induced contraction via inhibition of acetylcholinesterase activity in circular muscle strips of guinea pig stomachDrug Res. (Stuttg.)66(4),196-202(2016)
