Huperzine B
Cat. No.：YN380244
CAS No. ：103548-82-9
| 产品名称: | Huperzine B |
| CAS No.: | 103548-82-9 |
| Chemical Name: | 2,3,4,4aR,5R,6-hexahydro-12-methyl-1H-5,10bR-propeno-1,7-phenanthrolin-8(7H)-one |
| Synonyms: | |
| 分子量: | 256.34 |
| 分子式: | C₁₆H₂₀N₂O |
| SMILES: | CC1=C[C@]2([H])[C@]3([H])[C@](C(C=CC4=O)=C(N4)C2)(NCCC3)C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Huperzine B 是从Huperzia serrata中分离出的石蒜生物碱和高度选择性的乙酰胆碱酯酶 (AChE) 抑制剂。Huperzine B 可以用于改善阿尔茨海默氏病。 |
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Zhang, H.Y., and Tang, X.C.Huperzine B, a novel acetylcholinesterase inhibitor, attenuates hydrogen peroxide induced injury in PC12 cellsNeurosci. Lett.292(1),41-44(2000)
Feng, S., Xia, Y., Han, D., et al.Synthesis and acetylcholinesterase inhibition of derivatives of huperzine BBioorg. Med. Chem. Lett.15(3),523-526(2005)
Wang, X.-D., Chen, X.-Q., Yang, H.-H., et al.Comparison of the effects of cholinesterase inhibitors on [3H]MK-801 binding in rat cerebral cortexNeurosci. Lett.272(1),21-24(1999)
